Timing को बढ़ाने का इलाज . Premature Ejaculation Can Be Easily Treated With This Method [2aff85]
2025-07-30
Post Time: 2025-07-30
**Erectile dysfunction (ED)**, a common condition affecting millions worldwide, can significantly impact a man's quality of life. Among the various treatments available, **Cialis**, with its active ingredient **tadalafil**, stands out as a popular and effective option. This article delves into the mechanism of action of Cialis and how it helps men achieve and maintain an erection. ## The Physiology of an Erection Before understanding how Cialis works, it's crucial to grasp the basic physiology of an erection. An erection is a complex process involving the interplay of the nervous system, blood vessels, and hormones. Here’s a simplified breakdown: * **Sexual Stimulation:** Sexual arousal triggers the release of nitric oxide (NO) in the penile tissues. * **Nitric Oxide (NO):** NO activates an enzyme called guanylate cyclase. * **Guanylate Cyclase:** This enzyme increases the production of cyclic guanosine monophosphate (cGMP). * **cGMP:** cGMP causes the smooth muscles of the blood vessels in the penis to relax. * **Increased Blood Flow:** Relaxation of these muscles allows more blood to flow into the corpora cavernosa (the erectile tissues of the penis), resulting in an erection. * **Erection Maintenance:** As long as cGMP levels remain elevated, the erection persists. * **Erection Termination:** The enzyme phosphodiesterase type 5 (PDE5) breaks down cGMP, reducing blood flow and causing the erection to subside. ## How Cialis Works: Inhibiting PDE5 Cialis belongs to a class of drugs known as **PDE5 inhibitors**. Its primary mechanism involves the inhibition of PDE5, the enzyme responsible for breaking down cGMP. * **PDE5 Inhibition:** Tadalafil, the active ingredient in Cialis, selectively inhibits PDE5. * **Increased cGMP Levels:** By inhibiting PDE5, Cialis prevents the breakdown of cGMP, leading to increased levels of cGMP in the penis. * **Prolonged Muscle Relaxation:** The higher cGMP levels cause the smooth muscles in the penile arteries to remain relaxed for an extended period. * **Enhanced Blood Flow:** This prolonged muscle relaxation facilitates increased blood flow into the penis, resulting in a firm and sustained erection. * **Erection Occurs with Stimulation:** Importantly, Cialis does not cause an erection on its own; sexual stimulation is still required for the release of nitric oxide, which is necessary to initiate the process. ## The Advantage of Cialis: Duration of Action One of the distinguishing features of Cialis is its long duration of action. While other PDE5 inhibitors like Viagra (sildenafil) have an effective window of about 4-5 hours, Cialis can remain effective for up to **36 hours**, earning it the nickname "the weekend pill." * **Long Half-Life:** Tadalafil has a longer half-life compared to other PDE5 inhibitors, meaning it takes longer for the body to eliminate half of the drug. * **Flexibility in Timing:** This prolonged duration allows for more spontaneity in sexual activity, without having to plan too closely around the medication. * **Reduced Pressure:** The extended window of action reduces the pressure on couples, as they don’t have to time their sexual activity immediately after taking the medication. ## Clinical Efficacy of Cialis Clinical trials have demonstrated the efficacy of Cialis in treating ED. Here’s a summary of the key findings: | Trial Focus | Results | | :------------------------ | :-------------------------------------------------------------------------------- | | Improvement in Erection | Significant improvement in the ability to achieve and maintain an erection | | Successful Intercourse | Increased rates of successful sexual intercourse reported by patients | | Duration of Efficacy | Proven to be effective for up to 36 hours post-dosage | | Patient Satisfaction | Higher levels of patient satisfaction compared to placebo | | Dosage Response | Efficacy is dose-dependent, with higher doses providing a more robust response | ## Safety Profile and Side Effects While Cialis is generally safe and well-tolerated, some common side effects may occur: * **Headache:** A common side effect due to the vasodilation caused by tadalafil. * **Flushing:** Redness and a warm sensation in the face and neck, also due to vasodilation. * **Indigestion (Dyspepsia):** Stomach upset or discomfort. * **Nasal Congestion:** A stuffy nose. * **Muscle Aches (Myalgia):** Some men may experience mild to moderate muscle pain. * **Back Pain:** Lower back discomfort may occur. Rare but more serious side effects can include priapism (a prolonged and painful erection) and sudden vision or hearing changes. It's essential to consult a healthcare professional to determine if Cialis is a safe and appropriate treatment option, particularly if you have pre-existing medical conditions or take other medications. ## Dosage and Administration Cialis is available in different dosages, and the appropriate dosage will vary depending on the individual's specific needs and medical history. * **Typical Starting Dose:** The typical starting dose for Cialis is 10 mg, taken at least 30 minutes before sexual activity. * **Dosage Adjustments:** Depending on the individual's response and tolerance, the dosage may be adjusted to 5 mg or 20 mg. * **Daily Use Option:** Cialis is also available in lower doses (2.5 mg or 5 mg) for daily use, which is an option for those who anticipate frequent sexual activity. * **Prescription Required:** Cialis is a prescription medication, and it is vital to follow the instructions provided by your doctor or pharmacist. ## Conclusion Cialis, through its mechanism of action as a PDE5 inhibitor, effectively helps men with ED achieve and maintain erections by increasing blood flow to the penis. Its long duration of action provides greater spontaneity and flexibility compared to some other ED medications. However, it’s vital to use Cialis under the guidance of a healthcare provider to ensure safe and effective treatment. Always be aware of possible side effects and interactions with other drugs. By understanding its mechanism, potential benefits, and precautions, men can make informed decisions about using Cialis to improve their sexual health and overall quality of life. Premature Ejaculation Treatment : In this video, Dr. Rao is explaining about premature la pastilla viagra para qué sirve ejaculation ,one of the most common problem experienced by men. Doctors found a revolutionary treatment for premature ejaculation which involves injecting hyaluronic acid fillers into the penis. Fillers are the same type of filler that women often inject into their lips and many other areas to plump up a specific area. Fillers in Penis for PME: The goal of this treatment is to reduce sensitivity in the penis head (glans penis), for the life of the filler (usually between 18– 24 months duration in this area). The other use of filler is to increase the girth of the penis which gives instant results and is one of the safest way. An additional benefit extenze plus male enhancement tablets of the filler treatment is that your penis head will be larger, due to the added volume of the filler. The amount of filler required to reduce sensitivity will vary from person to person, but is usually around 2ml of filler. The filler can be dissolved at any stage if the reduction in sensitivity is too great, or you don’t like the result. Conversely, more filler can be injected to further decrease sensitivity in the head of the penis. Botox —It has been found that injecting Botox in the bulbospongiosus muscle of the penis can help delay ejaculation. The bulbospongiosus muscle is a superficial muscle which normally helps with erections, organism, and ejaculation. The mechanism of Botox is to temporarily relax muscles by disrupting the signaling between nerves and muscles where it is injected. The effect of botox lasts up to 6 months. Both the treatments are painless and patient is discharged immediately. It can be used in combination as well. Connect with us Call / WhatsApp 8882126505 / 9818565166 Dr. Rao Clinic H.no. 18, Friends Colony Near Sector 15, Part 1 Gurgaon Instagram: Instagram: YouTube: YouTube: Facebook: About Us: We are the finest Plastic and Cosmetic Surgery Centre which is run by country’s well known Plastic Surgeon. Dr. Udit Bhanu Rao is regarded amongst the most skilled and distinguished Plastic Surgeon of the country. He is extensively trained in plastic and aesthetic surgery at the prestigious Sir Ganga Ram Hospital, New Delhi. Dr.Rao regularly performs breast implant, breast fat grafting, liposuction, tummy tuck, breast reduction, rhinoplasty procedures, among red enhancers male pill others at his full-service clinic in Gurgaon. He is the number one choice for Aesthetic Genital Surgery which includes Penile Implant, Penile Lengthening and Girth Increase ,Vaginal Tightening, Hymenoplasty to name a few.Dr. Rao has over 15 years of medical training and experience .Dr. Rao is well known for pioneering the FUE technique in hair transplantation in India. He has been credited with over 10000 hair transplants in a short span of time.